eF-site ID 4aad-B PDB Code 4aad Chain B click to enlarge Title Crystal structure of the mutant D75N I-CreI in complex with its wild- type target in absence of metal ions at the active site (The four central bases, 2NN region, are composed by GTAC from 5' to 3') Classification HYDROLASE/DNA Compound DNA ENDONUCLEASE I-CREI Source null (4AAD) Sequence B:  NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSL TFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEI KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK FLEVCTWVDQIAALNDSKTRKTTSETVRAVLD Description Functional site 1) chain B residue 82 type sequence K description BINDING SITE FOR RESIDUE GOL B 1154 source : AC2 2) chain B residue 26 type sequence Q description BINDING SITE FOR RESIDUE GOL B 1155 source : AC3 3) chain B residue 28 type sequence K description BINDING SITE FOR RESIDUE GOL B 1155 source : AC3 4) chain B residue 42 type sequence T description BINDING SITE FOR RESIDUE GOL B 1155 source : AC3 5) chain B residue 79 type sequence S description BINDING SITE FOR RESIDUE GOL B 1155 source : AC3 6) chain B residue 20 type sequence D description BINDING SITE FOR RESIDUE GOL B 1156 source : AC4 7) chain B residue 46 type sequence T description BINDING SITE FOR RESIDUE GOL B 1156 source : AC4 8) chain B residue 19 type sequence G description BINDING SITE FOR RESIDUE GOL B 1157 source : AC7 9) chain B residue 21 type sequence G description BINDING SITE FOR RESIDUE GOL B 1157 source : AC7 10) chain B residue 22 type sequence S description BINDING SITE FOR RESIDUE GOL B 1157 source : AC7 11) chain B residue 98 type sequence K description BINDING SITE FOR RESIDUE GOL B 1157 source : AC7 12) chain B residue 107 type sequence K description BINDING SITE FOR RESIDUE GOL B 1158 source : AC8 13) chain B residue 110 type sequence E description BINDING SITE FOR RESIDUE GOL B 1158 source : AC8 14) chain B residue 19 type catalytic sequence G description 233 source MCSA : MCSA2 15) chain B residue 20 type catalytic sequence D description 233 source MCSA : MCSA2 16) chain B residue 19 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 17) chain B residue 20 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1

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