eF-site ID 4aa6-F
PDB Code 4aa6
Chain F

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Title The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Classification TRANSCRIPTION/DNA
Compound ESTROGEN RECEPTOR
Source (4AA6)
Sequence F:  TRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMC
PATNQCTIDKRKSCQACRLRKCYEVGMMK
Description (1)  ESTROGEN RECEPTOR


Functional site

1) chain F
residue 185
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 253
source : AC7

2) chain F
residue 188
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 253
source : AC7

3) chain F
residue 202
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 253
source : AC7

4) chain F
residue 205
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 253
source : AC7

5) chain F
residue 221
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 254
source : AC8

6) chain F
residue 227
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 254
source : AC8

7) chain F
residue 237
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 254
source : AC8

8) chain F
residue 240
type
sequence C
description BINDING SITE FOR RESIDUE ZN F 254
source : AC8

9) chain F
residue 185-250
type DNA_BIND
sequence CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPAT
NQCTIDKRKSCQACRLRKCYEVGM
description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI1

10) chain F
residue 185-205
type ZN_FING
sequence CAVCNDYASGYHYGVWSCEGC
description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI2

11) chain F
residue 221-245
type ZN_FING
sequence CPATNQCTIDKRKSCQACRLRKC
description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI2


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