eF-site ID 4aa6-E
PDB Code 4aa6
Chain E

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Title The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation
Classification TRANSCRIPTION/DNA
Compound ESTROGEN RECEPTOR
Source (4AA6)
Sequence E:  RYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGDYMCPAT
NQCTIDKNRRKSCQACRLRKCYEVGMMK
Description (1)  ESTROGEN RECEPTOR


Functional site

1) chain E
residue 185
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 253
source : AC5

2) chain E
residue 188
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 253
source : AC5

3) chain E
residue 202
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 253
source : AC5

4) chain E
residue 205
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 253
source : AC5

5) chain E
residue 221
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 254
source : AC6

6) chain E
residue 227
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 254
source : AC6

7) chain E
residue 237
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 254
source : AC6

8) chain E
residue 240
type
sequence C
description BINDING SITE FOR RESIDUE ZN E 254
source : AC6

9) chain E
residue 185-250
type DNA_BIND
sequence CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGDYMCPATNQ
CTIDKNRRKSCQACRLRKCYEVGM
description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI1

10) chain E
residue 185-205
type ZN_FING
sequence CAVCNDYASGYHYGVWSCEGC
description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI2

11) chain E
residue 221-245
type ZN_FING
sequence CPATNQCTIDKNRRKSCQACRLRKC
description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
source Swiss-Prot : SWS_FT_FI2


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