eF-site ID 4a69-A PDB Code 4a69 Chain A click to enlarge Title Structure of HDAC3 bound to corepressor and inositol tetraphosphate Classification TRANSCRIPTION Compound HISTONE DEACETYLASE 3, Source Homo sapiens (Human) (NCOR2_HUMAN) Sequence A:  AKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGL YKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGF TKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNK ICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYH PRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFP GTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVIN QVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVE YVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISE ELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQT IFENLKMLN Description Functional site 1) chain A residue 170 type sequence D description BINDING SITE FOR RESIDUE ZN A 500 source : AC1 2) chain A residue 172 type sequence H description BINDING SITE FOR RESIDUE ZN A 500 source : AC1 3) chain A residue 259 type sequence D description BINDING SITE FOR RESIDUE ZN A 500 source : AC1 4) chain A residue 134 type sequence H description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 5) chain A residue 135 type sequence H description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 6) chain A residue 143 type sequence G description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 7) chain A residue 170 type sequence D description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 8) chain A residue 172 type sequence H description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 9) chain A residue 259 type sequence D description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 10) chain A residue 296 type sequence G description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 11) chain A residue 298 type sequence Y description BINDING SITE FOR RESIDUE ACT A 501 source : AC2 12) chain A residue 168 type sequence D description BINDING SITE FOR RESIDUE K A 503 source : AC3 13) chain A residue 170 type sequence D description BINDING SITE FOR RESIDUE K A 503 source : AC3 14) chain A residue 172 type sequence H description BINDING SITE FOR RESIDUE K A 503 source : AC3 15) chain A residue 191 type sequence S description BINDING SITE FOR RESIDUE K A 503 source : AC3 16) chain A residue 192 type sequence F description BINDING SITE FOR RESIDUE K A 503 source : AC3 17) chain A residue 181 type sequence F description BINDING SITE FOR RESIDUE K A 504 source : AC4 18) chain A residue 184 type sequence T description BINDING SITE FOR RESIDUE K A 504 source : AC4 19) chain A residue 187 type sequence V description BINDING SITE FOR RESIDUE K A 504 source : AC4 20) chain A residue 217 type sequence Y description BINDING SITE FOR RESIDUE K A 504 source : AC4 21) chain A residue 113 type sequence Q description BINDING SITE FOR RESIDUE GOL A 505 source : AC5 22) chain A residue 116 type sequence T description BINDING SITE FOR RESIDUE GOL A 505 source : AC5 23) chain A residue 116 type sequence T description BINDING SITE FOR RESIDUE GOL A 506 source : AC6 24) chain A residue 119 type sequence N description BINDING SITE FOR RESIDUE GOL A 506 source : AC6 25) chain A residue 120 type sequence N description BINDING SITE FOR RESIDUE GOL A 506 source : AC6 26) chain A residue 156 type sequence E description BINDING SITE FOR RESIDUE GOL A 506 source : AC6 27) chain A residue 160 type sequence Y description BINDING SITE FOR RESIDUE GOL A 506 source : AC6 28) chain A residue 265 type sequence R description BINDING SITE FOR RESIDUE GOL B 505 source : BC2 29) chain A residue 17 type sequence H description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 30) chain A residue 21 type sequence G description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 31) chain A residue 25 type sequence K description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 32) chain A residue 265 type sequence R description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 33) chain A residue 300 type sequence V description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 34) chain A residue 301 type sequence R description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 35) chain A residue 331 type sequence Y description BINDING SITE FOR RESIDUE I0P C 501 source : BC4 36) chain A residue 116 type sequence T description BINDING SITE FOR RESIDUE I0P D 501 source : BC5 37) chain A residue 120 type sequence N description BINDING SITE FOR RESIDUE I0P D 501 source : BC5 38) chain A residue 135 type ACT_SITE sequence H description ACT_SITE => ECO:0000250|UniProtKB:Q13547 source Swiss-Prot : SWS_FT_FI1

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