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eF-site ID
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4a5w-A |
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PDB Code
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4a5w |
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Chain
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A |
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click to enlarge
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Title
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Crystal structure of C5b6 |
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Classification
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IMMUNE SYSTEM |
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Compound
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COMPLEMENT C5 |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
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A: |
TYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPD
KKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSY
VYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSV
KVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIG
IISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKE
YVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVVT
EADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF
DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAE
IPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQ
LVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFV
LNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLS
QSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNY
LILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLL
VYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADA
YSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLE
RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADD
SQENDEPCKEIRSYFPESWLWEVHLVPRRKQLQFALPDSL
TTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVV
RGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVID
HQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSL
ETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTIS
RRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQ
EGINILTHAEAELMSVVPVFYVFHYLETGNHWNIFHSDPL
IEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLT
AFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFK
ENSQLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTAL
IKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSI
VSALKREALVKGNPPIYRFWKDNLQHGTARMVETTAYALL
TSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEG
LTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGR
PVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCS
FYLKIDTQDIYKRIVACASYKPSREESSSGSSHAVMDISL
PTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIP
SSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMF
YSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETR
KQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTG
EAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIK
YNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFA
EDIFLNGC
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Description
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