eF-site ID 4a51-G PDB Code 4a51 Chain G click to enlarge Title Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence G:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKIGKLNLVDLAG SENNQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLG GRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP Description Functional site 1) chain G residue 226 type sequence T description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 2) chain G residue 227 type sequence L description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 3) chain G residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 4) chain G residue 26 type sequence R description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 5) chain G residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 6) chain G residue 106 type sequence Q description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 7) chain G residue 107 type sequence T description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 8) chain G residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 9) chain G residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 10) chain G residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 11) chain G residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 12) chain G residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 13) chain G residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 14) chain G residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP G 601 source : CC1 15) chain G residue 112 type sequence T description BINDING SITE FOR RESIDUE MG G 701 source : CC2 16) chain G residue 116 type sequence E description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 17) chain G residue 117 type sequence G description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 18) chain G residue 137 type sequence P description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 19) chain G residue 160 type sequence L description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 20) chain G residue 211 type sequence Y description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 21) chain G residue 214 type sequence L description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 22) chain G residue 215 type sequence E description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 23) chain G residue 218 type sequence A description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 24) chain G residue 221 type sequence R description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 25) chain G residue 229 type sequence N description BINDING SITE FOR RESIDUE CL G 1364 source : DC7 26) chain G residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 27) chain G residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

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