eF-site ID 4a51-F PDB Code 4a51 Chain F click to enlarge Title Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence F:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHKIGKLNLVDLAGS ENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSL GGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP Description Functional site 1) chain F residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 2) chain F residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 3) chain F residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 4) chain F residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 5) chain F residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 6) chain F residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 7) chain F residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 8) chain F residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 9) chain F residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP F 601 source : BC7 10) chain F residue 112 type sequence T description BINDING SITE FOR RESIDUE MG F 701 source : BC8 11) chain F residue 117 type sequence G description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 12) chain F residue 118 type sequence E description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 13) chain F residue 119 type sequence R description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 14) chain F residue 136 type sequence I description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 15) chain F residue 137 type sequence P description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 16) chain F residue 160 type sequence L description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 17) chain F residue 211 type sequence Y description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 18) chain F residue 214 type sequence L description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 19) chain F residue 215 type sequence E description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 20) chain F residue 218 type sequence A description BINDING SITE FOR RESIDUE DQ8 F 801 source : BC9 21) chain F residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 22) chain F residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

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