eF-site ID 4a51-E PDB Code 4a51 Chain E click to enlarge Title Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence E:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKVKIGKLNLVDL AGSENINQSLLTLGRVITALVERTPHVPYRESKLTRILQD SLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNK P Description Functional site 1) chain E residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 2) chain E residue 26 type sequence R description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 3) chain E residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 4) chain E residue 107 type sequence T description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 5) chain E residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 6) chain E residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 7) chain E residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 8) chain E residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 9) chain E residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 10) chain E residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP E 601 source : BC4 11) chain E residue 112 type sequence T description BINDING SITE FOR RESIDUE MG E 701 source : BC5 12) chain E residue 116 type sequence E description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 13) chain E residue 117 type sequence G description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 14) chain E residue 118 type sequence E description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 15) chain E residue 119 type sequence R description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 16) chain E residue 133 type sequence A description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 17) chain E residue 137 type sequence P description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 18) chain E residue 160 type sequence L description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 19) chain E residue 211 type sequence Y description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 20) chain E residue 214 type sequence L description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 21) chain E residue 215 type sequence E description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 22) chain E residue 218 type sequence A description BINDING SITE FOR RESIDUE DQ8 E 801 source : BC6 23) chain E residue 43 type sequence C description BINDING SITE FOR RESIDUE CL E 1364 source : DC6 24) chain E residue 73 type sequence G description BINDING SITE FOR RESIDUE CL E 1364 source : DC6 25) chain E residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 26) chain E residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

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