eF-site ID 4a51-D PDB Code 4a51 Chain D click to enlarge Title Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence D:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKEELVKIGKLNL VDLAGSENINQSLLTLGRVITALVERTPHVPYRESKLTRI LQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNI LN Description Functional site 1) chain D residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 2) chain D residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 3) chain D residue 107 type sequence T description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 4) chain D residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 5) chain D residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 6) chain D residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 7) chain D residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 8) chain D residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 9) chain D residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 10) chain D residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP D 601 source : BC1 11) chain D residue 112 type sequence T description BINDING SITE FOR RESIDUE MG D 701 source : BC2 12) chain D residue 265 type sequence D description BINDING SITE FOR RESIDUE MG D 701 source : BC2 13) chain D residue 116 type sequence E description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 14) chain D residue 117 type sequence G description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 15) chain D residue 118 type sequence E description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 16) chain D residue 136 type sequence I description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 17) chain D residue 137 type sequence P description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 18) chain D residue 160 type sequence L description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 19) chain D residue 211 type sequence Y description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 20) chain D residue 214 type sequence L description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 21) chain D residue 218 type sequence A description BINDING SITE FOR RESIDUE DQ8 D 801 source : BC3 22) chain D residue 42 type sequence E description BINDING SITE FOR RESIDUE SO4 D 1362 source : CC4 23) chain D residue 43 type sequence C description BINDING SITE FOR RESIDUE SO4 D 1362 source : CC4 24) chain D residue 74 type sequence A description BINDING SITE FOR RESIDUE SO4 D 1362 source : CC4 25) chain D residue 186 type sequence D description BINDING SITE FOR RESIDUE CL D 1363 source : DC4 26) chain D residue 318 type sequence R description BINDING SITE FOR RESIDUE CL D 1363 source : DC4 27) chain D residue 30 type sequence L description BINDING SITE FOR RESIDUE CL D 1364 source : DC5 28) chain D residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 29) chain D residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

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