eF-site ID 4a51-C PDB Code 4a51 Chain C click to enlarge Title Crystal structure of human kinesin Eg5 in complex with 1-(3-(((2-Aminoethyl)thio)diphenylmethyl)phenyl)ethanone hydrochloride Classification CELL CYCLE Compound KINESIN-LIKE PROTEIN KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence C:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKVKIGKLNLVDL AGSENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQ DSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILN KPEVN Description Functional site 1) chain C residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 2) chain C residue 26 type sequence R description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 3) chain C residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 4) chain C residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 5) chain C residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 6) chain C residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 7) chain C residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 8) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 9) chain C residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 10) chain C residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP C 601 source : AC7 11) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE MG C 701 source : AC8 12) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 13) chain C residue 116 type sequence E description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 14) chain C residue 117 type sequence G description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 15) chain C residue 118 type sequence E description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 16) chain C residue 119 type sequence R description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 17) chain C residue 136 type sequence I description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 18) chain C residue 137 type sequence P description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 19) chain C residue 160 type sequence L description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 20) chain C residue 211 type sequence Y description BINDING SITE FOR RESIDUE DQ8 C 801 source : AC9 21) chain C residue 124 type sequence E description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 22) chain C residue 125 type sequence Y description BINDING SITE FOR RESIDUE DQ8 G 801 source : CC3 23) chain C residue 47 type sequence R description BINDING SITE FOR RESIDUE SO4 D 1362 source : CC4 24) chain C residue 43 type sequence C description BINDING SITE FOR RESIDUE CL C 1367 source : DC1 25) chain C residue 354 type sequence H description BINDING SITE FOR RESIDUE CL C 1369 source : DC3 26) chain C residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 27) chain C residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

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