|
|
eF-site ID
|
4a49-B |
|
PDB Code
|
4a49 |
|
Chain
|
B |
|
click to enlarge
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Title
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Structure of phosphoTyr371-c-Cbl-UbcH5B complex |
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Classification
|
LIGASE |
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Compound
|
E3 ubiquitin-protein ligase CBL |
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Source
|
(UB2D2_HUMAN) |
|
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Sequence
|
B: |
ALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPN
DSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSN
GSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVP
EIARIYKTDREKYNRIAREWTQKYAM
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
7 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE K B 1148
|
| source |
: AC3
|
|
|
2)
|
chain |
B |
| residue |
7 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE K B 1148
|
| source |
: AC3
|
|
|
3)
|
chain |
B |
| residue |
74-89 |
| type |
prosite |
| sequence |
YHPNINSNGSICLDIL
|
| description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNInsn.GsICLdiL
|
| source |
prosite : PS00183
|
|
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4)
|
chain |
B |
| residue |
85 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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