eF-site ID 4a49-A
PDB Code 4a49
Chain A

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Title Structure of phosphoTyr371-c-Cbl-UbcH5B complex
Classification LIGASE
Compound E3 ubiquitin-protein ligase CBL
Source (UB2D2_HUMAN)
Sequence A:  DHIKVTQEQFELXCEMGSTFQLCKICAENDKDVKIEPCGH
LMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFD
Description


Functional site

1) chain A
residue 381
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1436
source : AC1

2) chain A
residue 384
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1436
source : AC1

3) chain A
residue 401
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1436
source : AC1

4) chain A
residue 404
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1436
source : AC1

5) chain A
residue 396
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1437
source : AC2

6) chain A
residue 398
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 1437
source : AC2

7) chain A
residue 416
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1437
source : AC2

8) chain A
residue 419
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 1437
source : AC2

9) chain A
residue 396-405
type prosite
sequence CGHLMCTSCL
description ZF_RING_1 Zinc finger RING-type signature. CgHlMCtsCL
source prosite : PS00518

10) chain A
residue 371
type MOD_RES
sequence X
description Phosphotyrosine; by INSR => ECO:0000269|PubMed:11997497
source Swiss-Prot : SWS_FT_FI2


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