eF-site ID 4a3f-A PDB Code 4a3f Chain A click to enlarge Title RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP Classification TRANSCRIPTION Compound DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 Source ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; Sequence A:  GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMD ETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFG HIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELM RQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLV SRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVL STEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVP PPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHN GAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPV KSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELD QVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGA KYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPV LFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADF DGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMG IVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPT PAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKD NGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVC AKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITET IAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFL NEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMS ACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVEN SYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLV KALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQS LDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGD LKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRR IIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRG KNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAF DWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLN TKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQ AKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEII QLHFSLQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTF KNDLFVIWSEDNDEKLIIRCRVVAEEDHMLKKIENTMLEN ITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDG VNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYK EVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFN RSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVIL GQMAPIGTGAFDVMIDEESLVKYMP Description (1)  DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 Functional site 1) chain A residue 446 type sequence R description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 2) chain A residue 448 type sequence P description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 3) chain A residue 479 type sequence N description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 4) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 5) chain A residue 1078 type sequence Q description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 6) chain A residue 1082 type sequence N description BINDING SITE FOR RESIDUE APC A 2455 source : AC1 7) chain A residue 107 type sequence C description BINDING SITE FOR RESIDUE ZN A 2456 source : AC2 8) chain A residue 110 type sequence C description BINDING SITE FOR RESIDUE ZN A 2456 source : AC2 9) chain A residue 148 type sequence C description BINDING SITE FOR RESIDUE ZN A 2456 source : AC2 10) chain A residue 167 type sequence C description BINDING SITE FOR RESIDUE ZN A 2456 source : AC2 11) chain A residue 67 type sequence C description BINDING SITE FOR RESIDUE ZN A 2457 source : AC3 12) chain A residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN A 2457 source : AC3 13) chain A residue 77 type sequence C description BINDING SITE FOR RESIDUE ZN A 2457 source : AC3 14) chain A residue 80 type sequence H description BINDING SITE FOR RESIDUE ZN A 2457 source : AC3 15) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE MG A 2458 source : AC4 16) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE MG A 2458 source : AC4 17) chain A residue 485 type sequence D description BINDING SITE FOR RESIDUE MG A 2458 source : AC4 18) chain A residue 483 type catalytic sequence D description 788 source MCSA : MCSA1 19) chain A residue 485 type catalytic sequence D description 788 source MCSA : MCSA1 20) chain A residue 483 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 21) chain A residue 485 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 22) chain A residue 107 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 23) chain A residue 110 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 24) chain A residue 148 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 25) chain A residue 167 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 26) chain A residue 481 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1

Display surface Download Links