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eF-site ID
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3zjv-A |
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PDB Code
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3zjv |
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Chain
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A |
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click to enlarge
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Title
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Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation |
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Classification
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LIGASE/RNA |
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Compound
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LEUCINE--TRNA LIGASE |
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Source
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null (3ZJV) |
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Sequence
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A: |
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSM
LPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYD
WSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVEIPQ
WFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGV
EITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQK
AAENNPELAAFIDECRNTMEKKGVDTGFKAVHPLTGEEIP
VWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPV
ILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAI
ADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLED
GTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVN
GMPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAAN
YWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEP
AKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKG
RIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGA
DTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYE
HTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRR
QTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVR
MLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDS
TLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYV
IYVPGKLLNLVVG
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Description
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Functional site
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1)
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chain |
A |
| residue |
622 |
| type |
BINDING |
| sequence |
K
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| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_00049
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
A |
| residue |
42-53 |
| type |
prosite |
| sequence |
PYPSGRLHMGHV
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| description |
AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGrLHMGHV
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| source |
prosite : PS00178
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