eF-site ID 3zjt-AB PDB Code 3zjt Chain A, B click to enlarge Title Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation Classification LIGASE/RNA Compound LEUCYL-TRNA SYNTHETASE Source Escherichia coli (strain K12) (3ZJT) Sequence A:  MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSM LPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYD WSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVEIPQ WFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGV EITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQK AAENNPELAAFIDECRNTEKKGVDTGFKAVHPLTGEEIPV WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI LAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIA DKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDG TVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG MPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANY WLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGR IVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEH TAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQ TFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRM LNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDST LVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLD GVTVRKVIYVPGKLLNLVVG B:  GGCCCGGAUGGUGGAAUCGGUAGACACAAGGGGAAUCCCU CGGCGUUCGCGCUGUGCGGGUUCAAGUCCCGCUCCGGGUA CCX Description Functional site 1) chain A residue 651 type sequence P description BINDING SITE FOR RESIDUE MG A 1861 source : AC1 2) chain A residue 723 type sequence N description BINDING SITE FOR RESIDUE MG A 1861 source : AC1 3) chain B residue 14 type sequence A description BINDING SITE FOR RESIDUE MG A 1861 source : AC1 4) chain B residue 15 type sequence A description BINDING SITE FOR RESIDUE MG A 1862 source : AC2 5) chain B residue 16 type sequence U description BINDING SITE FOR RESIDUE MG A 1862 source : AC2 6) chain B residue 19 type sequence G description BINDING SITE FOR RESIDUE MG A 1862 source : AC2 7) chain B residue 59 type sequence G description BINDING SITE FOR RESIDUE MG A 1862 source : AC2 8) chain B residue 60 type sequence U description BINDING SITE FOR RESIDUE MG A 1862 source : AC2 9) chain B residue 8 type sequence U description BINDING SITE FOR RESIDUE MG A 1863 source : AC3 10) chain B residue 9 type sequence G description BINDING SITE FOR RESIDUE MG A 1863 source : AC3 11) chain A residue 622 type BINDING sequence K description BINDING => ECO:0000255|HAMAP-Rule:MF_00049 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 42-53 type prosite sequence PYPSGRLHMGHV description AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGrLHMGHV source prosite : PS00178

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