eF-site ID 3zfo-A PDB Code 3zfo Chain A click to enlarge Title Crystal structure of substrate-like, unprocessed N-terminal protease Npro mutant S169P Classification HYDROLASE Compound N-TERMINAL PROTEASE NPRO Source Pestivirus strain D32/00_HoBi (Q5L4B1_9FLAV) Sequence A:  MEPLYDKNGAVLFGEPSDTHPQSTLKLPHPRGEKEVIVGI RDLPRKGDCRTGNRLGPVSGLFVKPGPVFYQDYSGPVYHR APLEQFKQAPMCEVTKRIGRVTGSDGNLYHMYVCTDGCIL VKTAKREGQDVLKWVYNVLDSPIWVTSCPV Description Functional site 1) chain A residue 138 type sequence C description BINDING SITE FOR RESIDUE SGM A 1171 source : AC1 2) chain A residue 154 type sequence W description BINDING SITE FOR RESIDUE SGM A 1171 source : AC1 3) chain A residue 155 type sequence V description BINDING SITE FOR RESIDUE SGM A 1171 source : AC1 4) chain A residue 21 type sequence M description BINDING SITE FOR RESIDUE CL A 1172 source : AC2 5) chain A residue 22 type sequence E description BINDING SITE FOR RESIDUE CL A 1172 source : AC2 6) chain A residue 105 type sequence Q description BINDING SITE FOR RESIDUE CL A 1172 source : AC2 7) chain A residue 66 type sequence K description BINDING SITE FOR RESIDUE OH A 1173 source : AC3 8) chain A residue 67 type sequence G description BINDING SITE FOR RESIDUE OH A 1173 source : AC3 9) chain A residue 68 type sequence D description BINDING SITE FOR RESIDUE OH A 1173 source : AC3

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