eF-site ID 3x08-B PDB Code 3x08 Chain B click to enlarge Title Crystal structure of PIP4KIIBETA N203A complex with GMP Classification TRANSFERASE Compound Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Source Homo sapiens (Human) (PI42B_HUMAN) Sequence B:  VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFK AYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGI DDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMH NILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVT RAVFSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDF LNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLV GIHDVDRAEQFGPGEFDPSVDVYAMKSHESSPKKEVYFMA IIDILTPEQYSKRFNEFMSNILT Description Functional site 1) chain B residue 96 type sequence K description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 2) chain B residue 98 type sequence Y description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 3) chain B residue 154 type sequence S description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 4) chain B residue 157 type sequence V description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 5) chain B residue 161 type sequence H description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 6) chain B residue 188 type sequence R description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 7) chain B residue 197 type sequence Y description BINDING SITE FOR RESIDUE 5GP A 502 source : AC2 8) chain B residue 203 type BINDING sequence A description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 9) chain B residue 214 type BINDING sequence K description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 10) chain B residue 369 type BINDING sequence D description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 150 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4 12) chain B residue 150 type catalytic sequence K description 662 source MCSA : MCSA2 13) chain B residue 278 type catalytic sequence D description 662 source MCSA : MCSA2 14) chain B residue 202 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X03 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 94 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P48426 source Swiss-Prot : SWS_FT_FI3

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