eF-site ID 3x03-B PDB Code 3x03 Chain B click to enlarge Title Crystal structure of PIP4KIIBETA complex with AMPPNP Classification TRANSFERASE Compound Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Source Homo sapiens (Human) (PI42B_HUMAN) Sequence B:  VKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFK AYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGI DDQDYQNSVTRSAPINRFLTTYDRRFVIKTVSSEDVAEMH NILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVT RNVFSHRLTVHRKYDLKGVAREASDKEKAKDLPTFKDNDF LNELHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIH DVDRAEQRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAI IDILTPEQYSKRFNEFMSNILT Description Functional site 1) chain B residue 139 type sequence F description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 2) chain B residue 148 type sequence V description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 3) chain B residue 202 type sequence R description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 4) chain B residue 203 type sequence N description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 5) chain B residue 204 type sequence V description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 6) chain B residue 282 type sequence L description BINDING SITE FOR RESIDUE ANP B 501 source : AC3 7) chain B residue 150 type catalytic sequence K description 662 source MCSA : MCSA2 8) chain B residue 278 type catalytic sequence D description 662 source MCSA : MCSA2 9) chain B residue 202 type BINDING sequence R description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X03 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 203 type BINDING sequence N description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 214 type BINDING sequence K description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 369 type BINDING sequence D description BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04 source Swiss-Prot : SWS_FT_FI2 13) chain B residue 94 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P48426 source Swiss-Prot : SWS_FT_FI3 14) chain B residue 150 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4

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