|
|
eF-site ID
|
3wzz-A |
|
PDB Code
|
3wzz |
|
Chain
|
A |
|
click to enlarge
|
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Title
|
Crystal structure of PIP4KIIBETA |
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Classification
|
TRANSFERASE |
|
Compound
|
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
|
Source
|
Homo sapiens (Human) (PI42B_HUMAN) |
|
|
Sequence
|
A: |
KVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDF
KAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFG
IDDQDYQNSVTRSAPINSTRFLTTYDRRFVIKTVSSEDVA
EMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYM
VVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTF
KDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMD
YSLLVGIHDVDRAEQEEMEVEERAEDEGPGEFDPSVDVYA
MKSHESSPKKEVYFMAIIDILTTVNPEQYSKRFNEFMSNI
LT
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|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
150 |
| type |
catalytic |
| sequence |
K
|
| description |
662
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
278 |
| type |
catalytic |
| sequence |
D
|
| description |
662
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
202 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X03
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
203 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
214 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
A |
| residue |
369 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000305|PubMed:26774281, ECO:0007744|PDB:3X04
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
94 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:P48426
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
A |
| residue |
150 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|