eF-site ID 3wj4-AB PDB Code 3wj4 Chain A, B click to enlarge Title Crystal structure of PPARgamma ligand binding domain in complex with tributyltin Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence A:  GSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPF VIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETDMSLHPLLQEIYK B:  GPLGSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKK SPFVIYDMNSLMMGEDKIKFKHKEVAIRIFQGCQFRSVEA VQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAV KFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDN LLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL LQVIKKTETDHPLLQEIYKD Description Functional site 1) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 2) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 3) chain A residue 327 type sequence Y description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 4) chain A residue 339 type sequence V description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 5) chain A residue 363 type sequence F description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 6) chain A residue 364 type sequence M description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 7) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 8) chain B residue 284 type sequence G description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 9) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 10) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 11) chain B residue 327 type sequence Y description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 12) chain B residue 330 type sequence L description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 13) chain B residue 339 type sequence V description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 14) chain B residue 353 type sequence L description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 15) chain B residue 363 type sequence F description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 16) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 17) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE TBY B 501 source : AC2 18) chain A residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 19) chain A residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 20) chain A residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 21) chain A residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 22) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 23) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 24) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 25) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 26) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 27) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links