eF-site ID 3wj4-A PDB Code 3wj4 Chain A click to enlarge Title Crystal structure of PPARgamma ligand binding domain in complex with tributyltin Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence A:  GSESADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPF VIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETDMSLHPLLQEIYK Description Functional site 1) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 2) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 3) chain A residue 327 type sequence Y description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 4) chain A residue 339 type sequence V description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 5) chain A residue 363 type sequence F description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 6) chain A residue 364 type sequence M description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 7) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE TBY A 501 source : AC1 8) chain A residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 9) chain A residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 10) chain A residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 11) chain A residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 12) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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