eF-site ID 3wha-B PDB Code 3wha Chain B click to enlarge Title Hsp90 alpha N-terminal domain in complex with a tricyclic inhibitor Classification Chaperone/chaperone Inhibitor Compound Heat shock protein HSP 90-alpha Source Homo sapiens (Human) (HS90A_HUMAN) Sequence B:  EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDA LDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTG IGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG VGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIG YPITLFVEK Description Functional site 1) chain B residue 55 type sequence A description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 2) chain B residue 93 type sequence D description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 3) chain B residue 96 type sequence I description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 4) chain B residue 97 type sequence G description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 5) chain B residue 98 type sequence M description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 6) chain B residue 106 type sequence N description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 7) chain B residue 107 type sequence L description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 8) chain B residue 138 type sequence F description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 9) chain B residue 139 type sequence Y description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 10) chain B residue 184 type sequence T description BINDING SITE FOR RESIDUE WHA B 301 source : AC3 11) chain B residue 51 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 12) chain B residue 93 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 13) chain B residue 138 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 14) chain B residue 112 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 15) chain B residue 58 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI3 16) chain B residue 84 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links