eF-site ID 3wc0-H PDB Code 3wc0 Chain H click to enlarge Title Crystal structure of C. albicans tRNA(His) guanylyltransferase (Thg1) with GTP Classification TRANSFERASE Compound Likely histidyl tRNA-specific guanylyltransferase Source Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (Q5AFK5_CANAL) Sequence H:  SKYEYVKLFEKENYLLPDTYIIIRVDGKGFHKFSQFYEFE KPNDLKALQVMNSAAEKLMSKYSDVMLAYGDSDEYSFLLR KNCQLYERREMKLTTLFSSLMSTYYMYFWSQYFPDKPLHI DHLPNFDARAVLYPDFKHIRNYFSWRQVDCHINNLYNTTF WNLVLKLKMTPQQAEQRLMGTVASDKNEILFKECGVNYNN ESEMYKKGTIIVREFENYETEDEAELSKRQVQRLEKKRKK AELKIYHVDIINDDSWWKSRPWLKD Description Functional site 1) chain H residue 7 type sequence E description BINDING SITE FOR RESIDUE GTP G 402 source : DC5 2) chain H residue 10 type sequence K description BINDING SITE FOR RESIDUE GTP G 402 source : DC5 3) chain H residue 92 type sequence R description BINDING SITE FOR RESIDUE GTP G 402 source : DC5 4) chain H residue 95 type sequence K description BINDING SITE FOR RESIDUE GTP G 402 source : DC5 5) chain H residue 95 type sequence K description BINDING SITE FOR RESIDUE MG G 405 source : DC8 6) chain H residue 29 type sequence D description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 7) chain H residue 30 type sequence G description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 8) chain H residue 32 type sequence G description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 9) chain H residue 33 type sequence F description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 10) chain H residue 34 type sequence H description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 11) chain H residue 37 type sequence S description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 12) chain H residue 42 type sequence F description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 13) chain H residue 43 type sequence E description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 14) chain H residue 44 type sequence K description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 15) chain H residue 45 type sequence P description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 16) chain H residue 47 type sequence D description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 17) chain H residue 75 type sequence S description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 18) chain H residue 76 type sequence D description BINDING SITE FOR RESIDUE GTP H 401 source : DC9 19) chain H residue 27 type sequence R description BINDING SITE FOR RESIDUE GTP H 402 source : EC1 20) chain H residue 132 type sequence R description BINDING SITE FOR RESIDUE GTP H 402 source : EC1 21) chain H residue 148 type sequence W description BINDING SITE FOR RESIDUE GTP H 402 source : EC1 22) chain H residue 29 type sequence D description BINDING SITE FOR RESIDUE MG H 403 source : EC2 23) chain H residue 76 type sequence D description BINDING SITE FOR RESIDUE MG H 403 source : EC2 24) chain H residue 77 type sequence E description BINDING SITE FOR RESIDUE MG H 403 source : EC2 25) chain H residue 29 type sequence D description BINDING SITE FOR RESIDUE MG H 404 source : EC3 26) chain H residue 30 type sequence G description BINDING SITE FOR RESIDUE MG H 404 source : EC3 27) chain H residue 76 type sequence D description BINDING SITE FOR RESIDUE MG H 404 source : EC3

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