|
|
eF-site ID
|
3w11-E |
|
PDB Code
|
3w11 |
|
Chain
|
E |
|
click to enlarge
|
|
|
Title
|
Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7 |
|
Classification
|
HORMONE/HORMONE RECEPTOR/IMMUNE SYSTEM |
|
Compound
|
Insulin A chain |
|
Source
|
(3W11) |
|
|
Sequence
|
E: |
GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPE
DFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRG
SRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNE
LCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICNCPAT
VINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC
LGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWR
CVNFSFCQDLHHKQYVIHNNKCIPECPSGYTMNSSNLLCT
PCLGPCPK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
25 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
2)
|
chain |
E |
| residue |
111 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
3)
|
chain |
E |
| residue |
255 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
E |
| residue |
78 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
E |
| residue |
295 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
6)
|
chain |
E |
| residue |
215 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:23302862
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
7)
|
chain |
E |
| residue |
39 |
| type |
SITE |
| sequence |
F
|
| description |
Insulin-binding => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
E |
| residue |
16 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862, ECO:0000269|PubMed:2983222
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|