eF-site ID 3vdz-A PDB Code 3vdz Chain A click to enlarge Title Tailoring Encodable Lanthanide-Binding Tags as MRI Contrast Agents: xq-dSE3-Ubiquitin at 2.4 Angstroms Classification METAL BINDING PROTEIN, DE NOVO DESIGN Compound Ubiquitin-40S ribosomal protein S27a Source (3VDZ) Sequence A:  GAGYIDTDNDGSIDGDELYIDTDNDGSIDGDELLAMQIFV KTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIF AGKQLEDGRTLSDYNIQKESTLHLVLRLRG Description Functional site 1) chain A residue 71 type sequence D description BINDING SITE FOR RESIDUE GD A 201 source : AC1 2) chain A residue 73 type sequence D description BINDING SITE FOR RESIDUE GD A 201 source : AC1 3) chain A residue 75 type sequence D description BINDING SITE FOR RESIDUE GD A 201 source : AC1 4) chain A residue 77 type sequence S description BINDING SITE FOR RESIDUE GD A 201 source : AC1 5) chain A residue 79 type sequence D description BINDING SITE FOR RESIDUE GD A 201 source : AC1 6) chain A residue 82 type sequence E description BINDING SITE FOR RESIDUE GD A 201 source : AC1 7) chain A residue 86 type sequence D description BINDING SITE FOR RESIDUE GD A 202 source : AC2 8) chain A residue 88 type sequence D description BINDING SITE FOR RESIDUE GD A 202 source : AC2 9) chain A residue 90 type sequence D description BINDING SITE FOR RESIDUE GD A 202 source : AC2 10) chain A residue 92 type sequence S description BINDING SITE FOR RESIDUE GD A 202 source : AC2 11) chain A residue 97 type sequence E description BINDING SITE FOR RESIDUE GD A 202 source : AC2 12) chain A residue 172 type sequence R description BINDING SITE FOR RESIDUE SO4 A 203 source : AC3 13) chain A residue 174 type sequence R description BINDING SITE FOR RESIDUE SO4 A 203 source : AC3 14) chain A residue 175 type sequence G description BINDING SITE FOR RESIDUE SO4 A 203 source : AC3 15) chain A residue 127 type sequence K description BINDING SITE FOR RESIDUE SO4 A 204 source : AC4 16) chain A residue 141 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 204 source : AC4 17) chain A residue 142 type sequence R description BINDING SITE FOR RESIDUE SO4 A 204 source : AC4 18) chain A residue 152 type sequence D description BINDING SITE FOR RESIDUE SO4 A 204 source : AC4 19) chain A residue 172 type sequence R description BINDING SITE FOR RESIDUE SO4 A 204 source : AC4 20) chain A residue 71-83 type prosite sequence DTDNDGSIDGDEL description EF_HAND_1 EF-hand calcium-binding domain. DTDNDGSIDgdEL source prosite : PS00018 21) chain A residue 86-98 type prosite sequence DTDNDGSIDGDEL description EF_HAND_1 EF-hand calcium-binding domain. DTDNDGSIDgdEL source prosite : PS00018 22) chain A residue 127-152 type prosite sequence KAKIQDKEGIPPDQQRLIFAGKQLED description UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD source prosite : PS00299 23) chain A residue 154 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 24) chain A residue 172 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 25) chain A residue 129 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 source Swiss-Prot : SWS_FT_FI10 26) chain A residue 133 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 source Swiss-Prot : SWS_FT_FI11 27) chain A residue 163 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 source Swiss-Prot : SWS_FT_FI12 28) chain A residue 168 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 29) chain A residue 165 type MOD_RES sequence S description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25474007, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 30) chain A residue 166 type MOD_RES sequence T description (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457 source Swiss-Prot : SWS_FT_FI4 31) chain A residue 106 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 source Swiss-Prot : SWS_FT_FI6 32) chain A residue 111 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 33) chain A residue 148 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 34) chain A residue 127 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 source Swiss-Prot : SWS_FT_FI9

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