eF-site ID 3v9t-AC PDB Code 3v9t Chain A, C click to enlarge Title Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Classification TRANSCRIPTION/TRANSCRIPTION REGULATOR Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PRGC1_HUMAN) Sequence A:  PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKS PFVIYDMNSLMMGEDKISKEVAIRIFQGCQFRSVEAVQEI TEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNK DGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNA LELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQA LELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVI KKTETSLHPLLQEIYKDL C:  SLLKKLLLAP Description Functional site 1) chain A residue 284 type sequence G description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 2) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 3) chain A residue 287 type sequence F description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 4) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 5) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 6) chain A residue 326 type sequence I description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 7) chain A residue 330 type sequence L description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 8) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 9) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 10) chain A residue 353 type sequence L description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 11) chain A residue 367 type sequence K description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 12) chain A residue 449 type sequence H description BINDING SITE FOR RESIDUE 17L A 501 source : AC1 13) chain C residue 11 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 323 type MOD_RES sequence H description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 449 type MOD_RES sequence H description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 16) chain A residue 473 type MOD_RES sequence Y description N6-acetyllysine => ECO:0000250|UniProtKB:O70343 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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