eF-site ID 3v64-ABCD PDB Code 3v64 Chain A, B, C, D click to enlarge Title Crystal Structure of agrin and LRP4 Classification PROTEIN BINDING Compound Low-density lipoprotein receptor-related protein 4 Source (AGRIN_RAT) Sequence A:  ALETLAFDGRTYIEYLNAVIESELTNEIPAEKALQSNHFE LSLRTEATQGLVLWIGKAAERADYMALAIVDGHLQLSYDL GSQPVVLRSTVKVNTNRWLRIRAHREHREGSLQVGNEAPV TGSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFV GCLRDVVVGHRQLHLLEDAVTKPELRPCPTP B:  LETLAFDGRTYIEYLNAVIESELTNEIPAEKALQSNHFEL SLRTEATQGLVLWIGKAAERADYMALAIVDGHLQLSYDLG SQPVVLRSTVKVNTNRWLRIRAHREHREGSLQVGNEAPVT GSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVG CLRDVVVGHRQLHLLEDAVTKPELRPCPTP C:  YCSQGCTNSFQCWCEAGYELRPDRRSCKALGPEPVLLFAN RIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSD VTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLY WTDSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEG TIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTID YAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAI TVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMD IHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPT GFRKINSHACALEVLFQG D:  YCSQGCTFQCWCEAGYELRPDRRSCKALGPEPVLLFANRI DIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVT LDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWT DSGTSRIEVANLDGAHRKVLLWQSLEKPRAIALHPMEGTI YWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYA GRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITV FEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIH TLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGF RKINSHACALEVLF Description (1)  agrin, Agrin Functional site 1) chain A residue 1831 type BINDING sequence L description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 2) chain A residue 1848 type BINDING sequence V description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 1898 type BINDING sequence G description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 1831 type BINDING sequence L description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 1848 type BINDING sequence V description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 6) chain B residue 1898 type BINDING sequence G description BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 1900 type BINDING sequence Q description BINDING => ECO:0007744|PDB:3V64 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 1900 type BINDING sequence Q description BINDING => ECO:0007744|PDB:3V64 source Swiss-Prot : SWS_FT_FI2 9) chain C residue 409-420 type prosite sequence CTNSFQCWC description ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CtNsegaFqCwC source prosite : PS00010 10) chain C residue 418-433 type prosite sequence CWCEAGYELRPDRRSC description EGF_2 EGF-like domain signature 2. CwCeaGYelrpdrrsC source prosite : PS01186 11) chain C residue 722-736 type prosite sequence CACPTGFRKINSHAC description EGF_2 EGF-like domain signature 2. CwCeaGYelrpdrrsC source prosite : PS01186 12) chain A residue 1783 type SITE sequence N description Highly important for the agrin receptor complex activity of the 'z(8)' insert source Swiss-Prot : SWS_FT_FI4 13) chain B residue 1783 type SITE sequence N description Highly important for the agrin receptor complex activity of the 'z(8)' insert source Swiss-Prot : SWS_FT_FI4 14) chain A residue 1779 type SITE sequence S description Alternative splice site to produce 'z' isoforms source Swiss-Prot : SWS_FT_FI3 15) chain B residue 1779 type SITE sequence S description Alternative splice site to produce 'z' isoforms source Swiss-Prot : SWS_FT_FI3

Display surface Download Links