|
|
eF-site ID
|
3v64-B |
|
PDB Code
|
3v64 |
|
Chain
|
B |
|
click to enlarge
|
|
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Title
|
Crystal Structure of agrin and LRP4 |
|
Classification
|
PROTEIN BINDING |
|
Compound
|
Low-density lipoprotein receptor-related protein 4 |
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Source
|
(AGRIN_RAT) |
|
|
Sequence
|
B: |
LETLAFDGRTYIEYLNAVIESELTNEIPAEKALQSNHFEL
SLRTEATQGLVLWIGKAAERADYMALAIVDGHLQLSYDLG
SQPVVLRSTVKVNTNRWLRIRAHREHREGSLQVGNEAPVT
GSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVG
CLRDVVVGHRQLHLLEDAVTKPELRPCPTP
|
|
|
Description
|
(1) |
agrin, Agrin
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
1831 |
| type |
BINDING |
| sequence |
L
|
| description |
BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
1848 |
| type |
BINDING |
| sequence |
V
|
| description |
BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
1898 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0007744|PDB:3V64, ECO:0007744|PDB:3V65
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
1900 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0007744|PDB:3V64
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
B |
| residue |
1783 |
| type |
SITE |
| sequence |
N
|
| description |
Highly important for the agrin receptor complex activity of the 'z(8)' insert
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
6)
|
chain |
B |
| residue |
1779 |
| type |
SITE |
| sequence |
S
|
| description |
Alternative splice site to produce 'z' isoforms
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|