eF-site ID 3v19-ABCD
PDB Code 3v19
Chain A, B, C, D

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Title Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Classification HORMONE
Compound Insulin
Source Homo sapiens (Human) (INS_HUMAN)
Sequence A:  GLLEQCCHSICSLYQLENYCN
B:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT
C:  GLLEQCCHSICSLYQLENYCN
D:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Description


Functional site

1) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 101
source : AC1

2) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 101
source : AC1

3) chain B
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN B 101
source : AC1

4) chain C
residue 6
type
sequence C
description BINDING SITE FOR RESIDUE IPH C 200
source : AC3

5) chain C
residue 9
type
sequence S
description BINDING SITE FOR RESIDUE IPH C 200
source : AC3

6) chain C
residue 10
type
sequence I
description BINDING SITE FOR RESIDUE IPH C 200
source : AC3

7) chain C
residue 11
type
sequence C
description BINDING SITE FOR RESIDUE IPH C 200
source : AC3

8) chain D
residue 11
type
sequence L
description BINDING SITE FOR RESIDUE IPH C 200
source : AC3

9) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 201
source : AC4

10) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 201
source : AC4

11) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE ZN D 201
source : AC4

12) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 202
source : AC5

13) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 202
source : AC5

14) chain D
residue 10
type
sequence H
description BINDING SITE FOR RESIDUE CL D 202
source : AC5

15) chain A
residue 6-20
type prosite
sequence CCHSICSLYQLENYC
description INSULIN Insulin family signature. CCHSiCSlyqLenyC
source prosite : PS00262


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