eF-site ID 3usg-A PDB Code 3usg Chain A click to enlarge Title Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles Classification TRANSPORT PROTEIN Compound Transporter Source null (O67854_AQUAE) Sequence A:  REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFM IPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLL WRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLV GLVPEPPTDPDSILRPFKEFLYSYIGVPKGDEPILKPSLF AYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAV FLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAA VGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNE KAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITL PAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFL EDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWA GTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRI YYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITR FYIIGLFLFLTFLVFLAERRRN Description Functional site 1) chain A residue 21 type sequence N description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 2) chain A residue 22 type sequence A description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 3) chain A residue 24 type sequence G description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 4) chain A residue 25 type sequence L description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 5) chain A residue 26 type sequence G description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 6) chain A residue 27 type sequence N description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 7) chain A residue 108 type sequence Y description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 8) chain A residue 253 type sequence F description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 9) chain A residue 254 type sequence T description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 10) chain A residue 256 type sequence S description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 11) chain A residue 259 type sequence F description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 12) chain A residue 359 type sequence I description BINDING SITE FOR RESIDUE LEU A 601 source : AC1 13) chain A residue 22 type sequence A description BINDING SITE FOR RESIDUE NA A 752 source : AC2 14) chain A residue 27 type sequence N description BINDING SITE FOR RESIDUE NA A 752 source : AC2 15) chain A residue 254 type sequence T description BINDING SITE FOR RESIDUE NA A 752 source : AC2 16) chain A residue 286 type sequence N description BINDING SITE FOR RESIDUE NA A 752 source : AC2 17) chain A residue 308 type sequence V description BINDING SITE FOR RESIDUE ACT A 520 source : AC3 18) chain A residue 201 type sequence T description BINDING SITE FOR RESIDUE UND A 522 source : AC4 19) chain A residue 204 type sequence I description BINDING SITE FOR RESIDUE UND A 522 source : AC4 20) chain A residue 87 type sequence N description BINDING SITE FOR RESIDUE PC A 523 source : AC5 21) chain A residue 88 type sequence R description BINDING SITE FOR RESIDUE PC A 523 source : AC5 22) chain A residue 20 type sequence G description BINDING SITE FOR RESIDUE NA A 524 source : AC6 23) chain A residue 23 type sequence V description BINDING SITE FOR RESIDUE NA A 524 source : AC6 24) chain A residue 24 type sequence G description BINDING SITE FOR RESIDUE NA A 524 source : AC6 25) chain A residue 351 type sequence A description BINDING SITE FOR RESIDUE NA A 524 source : AC6 26) chain A residue 354 type sequence T description BINDING SITE FOR RESIDUE NA A 524 source : AC6 27) chain A residue 355 type sequence S description BINDING SITE FOR RESIDUE NA A 524 source : AC6

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