eF-site ID 3upo-B PDB Code 3upo Chain B click to enlarge Title Structure of penicillin-binding protein A from M. tuberculosis: penicillin G acyl-enzyme complex Classification Penicillin-binding protein/Antibiotic Compound Penicillin-binding protein A Source Mycobacterium tuberculosis (PBPA_MYCTU) Sequence B:  SRQRGQITAGGQLLAYSVATDGRFRFLRVYPNPEVYAPVT GFYSLRYSSTALERAEDPILNGSDRRLFGRRLADFFTGRD PRGGNVDTTINPRIQQAGWDAMQQGCYGPCKGAVVALEPS TGKILALVSSPSYDPNLLASHNPEVQAQAWQRLGDNPASP LTNRAISETYPPGSTFKVITTAAALAAGATETEQLTAAPT IPLPGSTAQLENYGGAPCGDEPTVSLREAFVKSCNTAFVQ LGIRTGADALRSMARAFGLDSPPRPTPLQVAESTVGPIPD SAALGMTSIGQKDVALTPLANAEIAATIANGGITMRPYLV GSLKGPDLANISTTVRYQQRRAVSPQVAAKLTELMVGAEK VAQPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQAPK VAVAVLVENGADRLSATGGALAAPIGRAVIEAALQ Description Functional site 1) chain B residue 222 type sequence S description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 2) chain B residue 259 type sequence E description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 3) chain B residue 261 type sequence Y description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 4) chain B residue 281 type sequence S description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 5) chain B residue 283 type sequence N description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 6) chain B residue 425 type sequence T description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 7) chain B residue 426 type sequence G description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 8) chain B residue 427 type sequence T description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 9) chain B residue 472 type sequence G description BINDING SITE FOR RESIDUE PNM B 800 source : AC2 10) chain B residue 222 type ACT_SITE sequence S description Acyl-ester intermediate => ECO:0000250|UniProtKB:P0AD65 source Swiss-Prot : SWS_FT_FI1

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