eF-site ID 3ua9-B PDB Code 3ua9 Chain B click to enlarge Title Crystal structure of human tankyrase 2 in complex with a selective inhibitor Classification TRANSFERASE/TRANSFERASE INHIBITOR Compound Tankyrase-2 Source null (TNKS2_HUMAN) Sequence B:  GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNR YNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFH GSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQY VYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFS AMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLI TYQIMRPE Description Functional site 1) chain B residue 1081 type sequence C description BINDING SITE FOR RESIDUE ZN B 2 source : AC6 2) chain B residue 1084 type sequence H description BINDING SITE FOR RESIDUE ZN B 2 source : AC6 3) chain B residue 1089 type sequence C description BINDING SITE FOR RESIDUE ZN B 2 source : AC6 4) chain B residue 1092 type sequence C description BINDING SITE FOR RESIDUE ZN B 2 source : AC6 5) chain B residue 977 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1163 source : AC7 6) chain B residue 979 type sequence H description BINDING SITE FOR RESIDUE SO4 B 1163 source : AC7 7) chain B residue 980 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1163 source : AC7 8) chain B residue 1067 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1163 source : AC7 9) chain B residue 1070 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 1163 source : AC7 10) chain B residue 990 type sequence N description BINDING SITE FOR RESIDUE SO4 B 4 source : AC8 11) chain B residue 991 type sequence R description BINDING SITE FOR RESIDUE SO4 B 4 source : AC8 12) chain B residue 1160 type sequence P description BINDING SITE FOR RESIDUE SO4 B 4 source : AC8 13) chain B residue 1161 type sequence E description BINDING SITE FOR RESIDUE SO4 B 4 source : AC8 14) chain B residue 1031 type sequence H description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 15) chain B residue 1035 type sequence F description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 16) chain B residue 1038 type sequence A description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 17) chain B residue 1043 type sequence G description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 18) chain B residue 1044 type sequence F description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 19) chain B residue 1045 type sequence D description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 20) chain B residue 1048 type sequence H description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 21) chain B residue 1050 type sequence Y description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 22) chain B residue 1058 type sequence G description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 23) chain B residue 1060 type sequence Y description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 24) chain B residue 1075 type sequence I description BINDING SITE FOR RESIDUE IWR B 1 source : AC9 25) chain B residue 1006 type sequence W description BINDING SITE FOR RESIDUE PEG B 1164 source : BC1 26) chain B residue 1148 type sequence Y description BINDING SITE FOR RESIDUE PEG B 1164 source : BC1 27) chain B residue 1150 type sequence E description BINDING SITE FOR RESIDUE PEG B 1164 source : BC1 28) chain B residue 1081 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 29) chain B residue 1084 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 1089 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 1092 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links