eF-site ID 3u0z-B PDB Code 3u0z Chain B click to enlarge Title Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels Classification TRANSPORT PROTEIN Compound Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Source Mus musculus (Mouse) (HCN1_MOUSE) Sequence B:  DSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQ GKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANAD PNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVA GVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCR LYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNS Description Functional site 1) chain B residue 511 type sequence V description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 2) chain B residue 527 type sequence F description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 3) chain B residue 528 type sequence G description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 4) chain B residue 529 type sequence E description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 5) chain B residue 530 type sequence I description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 6) chain B residue 531 type sequence C description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 7) chain B residue 538 type sequence R description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 8) chain B residue 539 type sequence T description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 9) chain B residue 540 type sequence A description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 10) chain B residue 579 type sequence R description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 11) chain B residue 582 type sequence R description BINDING SITE FOR RESIDUE CMP B 646 source : AC2 12) chain B residue 528 type BINDING sequence G description BINDING => ECO:0000269|PubMed:22006928, ECO:0007744|PDB:3U0Z source Swiss-Prot : SWS_FT_FI1 13) chain B residue 538 type BINDING sequence R description BINDING => ECO:0000269|PubMed:22006928, ECO:0007744|PDB:3U0Z source Swiss-Prot : SWS_FT_FI1 14) chain B residue 579 type BINDING sequence R description BINDING => ECO:0000269|PubMed:22006928, ECO:0007744|PDB:3U0Z source Swiss-Prot : SWS_FT_FI1

Display surface Download Links