eF-site ID 3ty0-B PDB Code 3ty0 Chain B click to enlarge Title Structure of PPARgamma ligand binding domain in complex with (R)-5-(3-((3-(6-methoxybenzo[d]isoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-5-methyloxazolidine-2,4-dione Classification TRANSCRIPTION REGULATOR Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence B:  GSQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGK TTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIR IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKY GVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPF GDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGL LNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMT DLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY Description Functional site 1) chain B residue 764 type sequence F description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 2) chain B residue 766 type sequence H description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 3) chain B residue 784 type sequence G description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 4) chain B residue 785 type sequence C description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 5) chain B residue 788 type sequence R description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 6) chain B residue 789 type sequence S description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 7) chain B residue 792 type sequence A description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 8) chain B residue 826 type sequence I description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 9) chain B residue 829 type sequence M description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 10) chain B residue 830 type sequence L description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 11) chain B residue 833 type sequence L description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 12) chain B residue 841 type sequence I description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 13) chain B residue 842 type sequence S description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 14) chain B residue 864 type sequence M description BINDING SITE FOR RESIDUE 082 B 2 source : AC2 15) chain B residue 786 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain B residue 823 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 17) chain B residue 949 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 18) chain B residue 973 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 19) chain B residue 724 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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