eF-site ID 3tkj-B PDB Code 3tkj Chain B click to enlarge Title Crystal Structure of Human Asparaginase-like Protein 1 Thr168Ala Classification HYDROLASE Compound L-asparaginase Source Homo sapiens (Human) (ASGL1_HUMAN) Sequence B:  GNPIVVVHGGGAGPISKDRKERVHQGMVRAATVGYGILRE GGSAVDAVEGAVVALEDDPEFNAGCGSVLNTNGEVEMDAS IMDGKDLSAGAVSAVQCIANPIKLARLVMEKTPHCFLTDQ GAAQFAAAMGVPEIPGEKLVTERNKKRLEKEKHELGAVGA VALDCKGNVAYATSTGGIVNKMVGRVGDSPCLGAGGYADN DIGAVSTTGHGESILKVNLARLTLFHIEQGKTVEEAADLS LGYMKSRVKGLGGLIVVSKTGDWVAKWTSTSMPWAAAKDG KLHFGIDPDDTTITDLP Description Functional site 1) chain B residue 57 type sequence D description BINDING SITE FOR RESIDUE TAM A 402 source : AC2 2) chain B residue 100 type sequence N description BINDING SITE FOR RESIDUE TAM A 402 source : AC2 3) chain B residue 55 type sequence L description BINDING SITE FOR RESIDUE NA B 401 source : AC4 4) chain B residue 56 type sequence E description BINDING SITE FOR RESIDUE NA B 401 source : AC4 5) chain B residue 58 type sequence D description BINDING SITE FOR RESIDUE NA B 401 source : AC4 6) chain B residue 61 type sequence F description BINDING SITE FOR RESIDUE NA B 401 source : AC4 7) chain B residue 63 type sequence A description BINDING SITE FOR RESIDUE NA B 401 source : AC4 8) chain B residue 65 type sequence C description BINDING SITE FOR RESIDUE NA B 401 source : AC4 9) chain B residue 2 type sequence N description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 10) chain B residue 3 type sequence P description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 11) chain B residue 35 type sequence Y description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 12) chain B residue 39 type sequence R description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 13) chain B residue 289 type sequence K description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 14) chain B residue 290 type sequence D description BINDING SITE FOR RESIDUE TAM B 402 source : AC5 15) chain B residue 186 type sequence T description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 16) chain B residue 188 type sequence G description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 17) chain B residue 196 type sequence R description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 18) chain B residue 198 type sequence G description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 19) chain B residue 199 type sequence D description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 20) chain B residue 200 type sequence S description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 21) chain B residue 222 type sequence G description BINDING SITE FOR RESIDUE SO4 B 403 source : AC6 22) chain B residue 196 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 23) chain B residue 219 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI2 24) chain B residue 168 type ACT_SITE sequence A description Nucleophile => ECO:0000269|PubMed:19839645, ECO:0000269|PubMed:22861376 source Swiss-Prot : SWS_FT_FI1

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