|
eF-site ID
|
3tj6-AB |
PDB Code
|
3tj6 |
Chain
|
A, B |
|
click to enlarge
|
|
Title
|
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii |
Classification
|
protein binding/toxin |
Compound
|
Vinculin |
Source
|
Homo sapiens (Human) (B0BXR4_RICRO) |
|
Sequence
|
A: |
MPVFHTRTIESILEPVAQQISHLVIMHEEGKAIPDLTAPV
AAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENA
CTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLL
TFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNL
GPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPV
LISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEI
IRVLQLTSWDEDA
|
B: |
DDIYNKAREVINAVNPVIEALEK
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
162-182 |
type |
prosite |
sequence |
KNLGPGMTKMAKMIDERQQEL
|
description |
VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL
|
source |
prosite : PS00663
|
|
2)
|
chain |
A |
residue |
97 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine => ECO:0000250|UniProtKB:P85972
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
A |
residue |
173 |
type |
MOD_RES |
sequence |
K
|
description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|