eF-site ID 3tf6-ABC PDB Code 3tf6 Chain A, B, C click to enlarge Title Crystal structure of Neutrophil gelatinase-associated lipocalin (C87S mutant) in complex with Europium and the siderophore analog tren(cam)(1,2-hopo)2 Classification ANTIMICROBIAL PROTEIN Compound Neutrophil gelatinase-associated lipocalin Source (NGAL_HUMAN) Sequence A:  STSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAIL REDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRT FVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVF FKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLP ENHIVFPVPIDQCIDG B:  SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILRE DPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPG SQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKV SQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHI VFPVPIDQCID C:  SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILRE DKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFV PGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFK KVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPEN HIVFPVPIDQCID Description (1)  Neutrophil gelatinase-associated lipocalin Functional site 1) chain A residue 42 type sequence L description BINDING SITE FOR RESIDUE GOL A 201 source : AC1 2) chain A residue 164 type sequence N description BINDING SITE FOR RESIDUE GOL A 201 source : AC1 3) chain A residue 165 type sequence H description BINDING SITE FOR RESIDUE GOL A 201 source : AC1 4) chain C residue 75 type sequence K description BINDING SITE FOR RESIDUE GOL A 201 source : AC1 5) chain A residue 106 type sequence Y description BINDING SITE FOR RESIDUE DBH A 216 source : AC3 6) chain A residue 123 type sequence F description BINDING SITE FOR RESIDUE DBH A 216 source : AC3 7) chain A residue 125 type sequence K description BINDING SITE FOR RESIDUE DBH A 216 source : AC3 8) chain A residue 132 type sequence Y description BINDING SITE FOR RESIDUE DBH A 216 source : AC3 9) chain A residue 134 type sequence K description BINDING SITE FOR RESIDUE DBH A 216 source : AC3 10) chain A residue 52 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 11) chain A residue 54 type sequence T description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 12) chain A residue 68 type sequence S description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 13) chain A residue 81 type sequence R description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 14) chain A residue 123 type sequence F description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 15) chain A residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 16) chain A residue 136 type sequence T description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 17) chain A residue 138 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 221 source : AC4 18) chain B residue 125 type sequence K description BINDING SITE FOR RESIDUE EU B 206 source : AC5 19) chain B residue 106 type sequence Y description BINDING SITE FOR RESIDUE DBH B 216 source : AC6 20) chain B residue 123 type sequence F description BINDING SITE FOR RESIDUE DBH B 216 source : AC6 21) chain B residue 134 type sequence K description BINDING SITE FOR RESIDUE DBH B 216 source : AC6 22) chain B residue 33 type sequence V description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 23) chain B residue 52 type sequence Y description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 24) chain B residue 54 type sequence T description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 25) chain B residue 81 type sequence R description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 26) chain B residue 123 type sequence F description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 27) chain B residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 28) chain B residue 136 type sequence T description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 29) chain B residue 138 type sequence Y description BINDING SITE FOR RESIDUE SO4 B 221 source : AC7 30) chain A residue 75 type sequence K description BINDING SITE FOR RESIDUE GOL C 201 source : AC8 31) chain C residue 42 type sequence L description BINDING SITE FOR RESIDUE GOL C 201 source : AC8 32) chain C residue 164 type sequence N description BINDING SITE FOR RESIDUE GOL C 201 source : AC8 33) chain C residue 165 type sequence H description BINDING SITE FOR RESIDUE GOL C 201 source : AC8 34) chain C residue 106 type sequence Y description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 35) chain C residue 123 type sequence F description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 36) chain C residue 125 type sequence K description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 37) chain C residue 132 type sequence Y description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 38) chain C residue 133 type sequence F description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 39) chain C residue 134 type sequence K description BINDING SITE FOR RESIDUE DBH C 216 source : BC1 40) chain C residue 52 type sequence Y description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 41) chain C residue 54 type sequence T description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 42) chain C residue 68 type sequence S description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 43) chain C residue 81 type sequence R description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 44) chain C residue 123 type sequence F description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 45) chain C residue 134 type sequence K description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 46) chain C residue 138 type sequence Y description BINDING SITE FOR RESIDUE SO4 C 221 source : BC2 47) chain C residue 93 type sequence T description BINDING SITE FOR RESIDUE GOL C 183 source : BC3 48) chain C residue 94 type sequence L description BINDING SITE FOR RESIDUE GOL C 183 source : BC3 49) chain C residue 97 type sequence I description BINDING SITE FOR RESIDUE GOL C 183 source : BC3 50) chain C residue 105 type sequence S description BINDING SITE FOR RESIDUE GOL C 183 source : BC3 51) chain C residue 106 type sequence Y description BINDING SITE FOR RESIDUE GOL C 183 source : BC3 52) chain A residue 117 type sequence Q description BINDING SITE FOR RESIDUE GOL C 184 source : BC4 53) chain C residue 114 type sequence N description BINDING SITE FOR RESIDUE GOL C 184 source : BC4 54) chain C residue 118 type sequence H description BINDING SITE FOR RESIDUE GOL C 184 source : BC4 55) chain C residue 146 type sequence S description BINDING SITE FOR RESIDUE CL C 185 source : BC5 56) chain A residue 146 type sequence S description BINDING SITE FOR RESIDUE CL A 183 source : BC6 57) chain C residue 163 type sequence E description BINDING SITE FOR RESIDUE CL C 186 source : BC7 58) chain C residue 120 type sequence M description BINDING SITE FOR RESIDUE CL C 187 source : BC8 59) chain B residue 75 type sequence K description BINDING SITE FOR RESIDUE CL B 183 source : BC9 60) chain A residue 52 type BINDING sequence Y description BINDING => ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI1 61) chain B residue 52 type BINDING sequence Y description BINDING => ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI1 62) chain C residue 52 type BINDING sequence Y description BINDING => ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI1 63) chain A residue 106 type BINDING sequence Y description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 64) chain A residue 134 type BINDING sequence K description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 65) chain B residue 106 type BINDING sequence Y description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 66) chain B residue 134 type BINDING sequence K description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 67) chain C residue 106 type BINDING sequence Y description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 68) chain C residue 134 type BINDING sequence K description BINDING => ECO:0007744|PDB:3CMP source Swiss-Prot : SWS_FT_FI2 69) chain A residue 125 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 70) chain A residue 138 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 71) chain B residue 125 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 72) chain B residue 138 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 73) chain C residue 125 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 74) chain C residue 138 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U source Swiss-Prot : SWS_FT_FI3 75) chain A residue 21-34 type prosite sequence NFQDNQFQGKWYVV description LIPOCALIN Lipocalin signature. NFQdnQFQGKWYVV source prosite : PS00213 76) chain A residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10684642, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7683678, ECO:0007744|PDB:1DFV, ECO:0007744|PDB:1QQS source Swiss-Prot : SWS_FT_FI5 77) chain B residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10684642, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7683678, ECO:0007744|PDB:1DFV, ECO:0007744|PDB:1QQS source Swiss-Prot : SWS_FT_FI5 78) chain C residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10684642, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7683678, ECO:0007744|PDB:1DFV, ECO:0007744|PDB:1QQS source Swiss-Prot : SWS_FT_FI5

Display surface Download Links