eF-site/Summary 3tbl-D

eF-site ID	3tbl-D
PDB Code	3tbl
Chain	D

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Title	Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki Fragment Maturation
Classification	REPLICATION
Compound	Proliferating cell nuclear antigen
Source	(RS27A_HUMAN)

Sequence	D:	IFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQR LIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR

Description

Functional site


1)	chain	D
	residue	63
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16543144, ECO:0000269\|PubMed:18719106
	source	Swiss-Prot : SWS_FT_FI12

2)	chain	D
	residue	11
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

3)	chain	D
	residue	48
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

4)	chain	D
	residue	29
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16543144, ECO:0000269\|PubMed:25752573, ECO:0000269\|PubMed:25752577, ECO:0000269\|PubMed:34239127
	source	Swiss-Prot : SWS_FT_FI10

5)	chain	D
	residue	27
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305\|PubMed:15466860
	source	Swiss-Prot : SWS_FT_FI9

6)	chain	D
	residue	33
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:25752577
	source	Swiss-Prot : SWS_FT_FI11

7)	chain	D
	residue	27-52
	type	prosite
	sequence	KAKIQDKEGIPPDQQRLIFAGKQLED
	description	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
	source	prosite : PS00299

8)	chain	D
	residue	6
	type	CROSSLNK
	sequence	K
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733
	source	Swiss-Prot : SWS_FT_FI6