|
|
eF-site ID
|
3t3m-ABCDEFHL |
|
PDB Code
|
3t3m |
|
Chain
|
A, B, C, D, E, F, H, L |
|
click to enlarge
|
|
|
Title
|
A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS |
|
Classification
|
CELL ADHESION |
|
Compound
|
Integrin alpha-IIb |
|
Source
|
(3T3M) |
|
|
Sequence
|
A: |
LNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAP
RTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG
SQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTE
EAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDF
SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPV
ADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVA
VGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRL
RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADR
KLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAI
APLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR
SRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAY
GANQVAVYRAQPVV
|
| B: |
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDL
KENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQV
TQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDL
SYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKP
VSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQV
TRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRN
DASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNH
YSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQN
YSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVR
DLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIE
AKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQ
AEPNSHRCNNGNGTFECGVCRCGPGW
|
| C: |
LNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAP
RTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG
SQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTE
EAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDF
SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPV
ADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVA
VGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRL
RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADR
KLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAI
APLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR
SRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAY
GANQVAVYRAQPV
|
| D: |
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDL
KENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQV
TQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDL
SYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKP
VSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQV
TRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRN
DASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNH
YSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQN
YSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVR
DLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIE
AKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQ
AEPNSHRCNNGNGTFECGVCRCGPGWLGSQC
|
| E: |
EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQR
PEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAY
LQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSSA
KTTAPSVYPLAPVCSSVTLGCLVKGYFPEPVTLTWNSGSL
SSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAH
PASSTKVDKKIEPR
|
| F: |
DILMTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKP
GKSFMGLIYYGTNLVDGVPSRFSGSGSGADYSLTISSLDS
EDFADYYCVQYAQLPYTFGGGTKLEIKRADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRNEC
|
| H: |
EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQR
PEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAY
LQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSSA
KTTAPSVYPLAPVCTGSSVTLGCLVKGYFPEPVTLTWNSG
SLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNV
AHPASSTKVDKKIEPR
|
| L: |
DILMTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKP
GKSFMGLIYYGTNLVDGVPSRFSGSGSGADYSLTISSLDS
EDFADYYCVQYAQLPYTFGGGTKLEIKRADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRNEC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
158 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
2)
|
chain |
B |
| residue |
215 |
| type |
BINDING |
| sequence |
N
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
3)
|
chain |
B |
| residue |
217 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
B |
| residue |
219 |
| type |
BINDING |
| sequence |
P
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
D |
| residue |
158 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
6)
|
chain |
D |
| residue |
215 |
| type |
BINDING |
| sequence |
N
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
7)
|
chain |
D |
| residue |
217 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
8)
|
chain |
D |
| residue |
219 |
| type |
BINDING |
| sequence |
P
|
| description |
in LIMBS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
9)
|
chain |
B |
| residue |
251 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0007744|PDB:4G1M
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
10)
|
chain |
D |
| residue |
251 |
| type |
BINDING |
| sequence |
D
|
| description |
in LIMBS binding site => ECO:0007744|PDB:4G1M
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
11)
|
chain |
B |
| residue |
335 |
| type |
BINDING |
| sequence |
M
|
| description |
in ADMIDAS binding site and unliganded-closed conformation => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
12)
|
chain |
D |
| residue |
335 |
| type |
BINDING |
| sequence |
M
|
| description |
in ADMIDAS binding site and unliganded-closed conformation => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
13)
|
chain |
B |
| residue |
99 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
14)
|
chain |
D |
| residue |
99 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
15)
|
chain |
B |
| residue |
320 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
16)
|
chain |
B |
| residue |
371 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
17)
|
chain |
D |
| residue |
320 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
18)
|
chain |
D |
| residue |
371 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
19)
|
chain |
B |
| residue |
452 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
20)
|
chain |
D |
| residue |
452 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
21)
|
chain |
A |
| residue |
252 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
22)
|
chain |
A |
| residue |
297 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
23)
|
chain |
A |
| residue |
299 |
| type |
BINDING |
| sequence |
N
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
24)
|
chain |
A |
| residue |
301 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
25)
|
chain |
C |
| residue |
432 |
| type |
BINDING |
| sequence |
Y
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
26)
|
chain |
C |
| residue |
434 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
27)
|
chain |
B |
| residue |
121 |
| type |
BINDING |
| sequence |
S
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
28)
|
chain |
B |
| residue |
220 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
29)
|
chain |
D |
| residue |
121 |
| type |
BINDING |
| sequence |
S
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
30)
|
chain |
D |
| residue |
220 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
31)
|
chain |
A |
| residue |
303 |
| type |
BINDING |
| sequence |
R
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
32)
|
chain |
A |
| residue |
305 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
33)
|
chain |
A |
| residue |
365 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
34)
|
chain |
A |
| residue |
367 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
35)
|
chain |
A |
| residue |
369 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
36)
|
chain |
A |
| residue |
371 |
| type |
BINDING |
| sequence |
Y
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
37)
|
chain |
A |
| residue |
373 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
38)
|
chain |
A |
| residue |
426 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
39)
|
chain |
A |
| residue |
428 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
40)
|
chain |
A |
| residue |
430 |
| type |
BINDING |
| sequence |
N
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
41)
|
chain |
A |
| residue |
432 |
| type |
BINDING |
| sequence |
Y
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
42)
|
chain |
A |
| residue |
434 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
43)
|
chain |
C |
| residue |
243 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
44)
|
chain |
C |
| residue |
245 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
45)
|
chain |
C |
| residue |
247 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
46)
|
chain |
C |
| residue |
250 |
| type |
BINDING |
| sequence |
T
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
47)
|
chain |
C |
| residue |
252 |
| type |
BINDING |
| sequence |
E
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
48)
|
chain |
C |
| residue |
297 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
49)
|
chain |
C |
| residue |
299 |
| type |
BINDING |
| sequence |
N
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
50)
|
chain |
C |
| residue |
301 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
51)
|
chain |
C |
| residue |
303 |
| type |
BINDING |
| sequence |
R
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
52)
|
chain |
C |
| residue |
305 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
53)
|
chain |
C |
| residue |
365 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
54)
|
chain |
C |
| residue |
367 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
55)
|
chain |
C |
| residue |
369 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
56)
|
chain |
C |
| residue |
371 |
| type |
BINDING |
| sequence |
Y
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
57)
|
chain |
C |
| residue |
373 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
58)
|
chain |
C |
| residue |
426 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
59)
|
chain |
C |
| residue |
428 |
| type |
BINDING |
| sequence |
D
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
60)
|
chain |
C |
| residue |
430 |
| type |
BINDING |
| sequence |
N
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
61)
|
chain |
B |
| residue |
123 |
| type |
BINDING |
| sequence |
S
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
62)
|
chain |
D |
| residue |
123 |
| type |
BINDING |
| sequence |
S
|
| description |
in MIDAS binding site => ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCU
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
63)
|
chain |
D |
| residue |
126 |
| type |
BINDING |
| sequence |
D
|
| description |
in ADMIDAS binding site => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
64)
|
chain |
D |
| residue |
127 |
| type |
BINDING |
| sequence |
D
|
| description |
in ADMIDAS binding site => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
65)
|
chain |
B |
| residue |
126 |
| type |
BINDING |
| sequence |
D
|
| description |
in ADMIDAS binding site => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
66)
|
chain |
B |
| residue |
127 |
| type |
BINDING |
| sequence |
D
|
| description |
in ADMIDAS binding site => ECO:0000269|PubMed:11546839, ECO:0000269|PubMed:15378069, ECO:0000269|PubMed:19111664, ECO:0000269|PubMed:19704023, ECO:0007744|PDB:1JV2, ECO:0007744|PDB:1TYE, ECO:0007744|PDB:3FCS, ECO:0007744|PDB:3FCU, ECO:0007744|PDB:3IJE
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
67)
|
chain |
F |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
|
|
|
|