eF-site ID 3t03-B PDB Code 3t03 Chain B click to enlarge Title Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16 Classification TRANSCRIPTION/TRANSCRIPTION REGULATOR Compound Peroxisome proliferator-activated receptor gamma Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence B:  DLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVI YDMNSLMMGEKEVAIRIFQGCQFRSVEAVQEITEYAKSIP GFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEG QGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLN HPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTELHPL LQEIYKDLY Description Functional site 1) chain B residue 309 type sequence I description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 2) chain B residue 313 type sequence C description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 3) chain B residue 316 type sequence R description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 4) chain B residue 317 type sequence S description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 5) chain B residue 320 type sequence A description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 6) chain B residue 354 type sequence I description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 7) chain B residue 358 type sequence L description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 8) chain B residue 361 type sequence L description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 9) chain B residue 369 type sequence I description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 10) chain B residue 376 type sequence M description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 11) chain B residue 381 type sequence L description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 12) chain B residue 391 type sequence F description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 13) chain B residue 392 type sequence M description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 14) chain B residue 395 type sequence K description BINDING SITE FOR RESIDUE 3T0 B 1 source : AC2 15) chain B residue 314 type MOD_RES sequence Q description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 351 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 17) chain B residue 477 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 501 type MOD_RES sequence Y description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 252 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links