eF-site ID 3svh-A PDB Code 3svh Chain A click to enlarge Title Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand Classification UNKNOWN FUNCTION Compound CREB-binding protein Source Homo sapiens (Human) (CBP_HUMAN) Sequence A:  RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL GIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLM FNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG Description Functional site 1) chain A residue 1091 type sequence R description BINDING SITE FOR RESIDUE KRG A 1 source : AC1 2) chain A residue 1095 type sequence M description BINDING SITE FOR RESIDUE KRG A 1 source : AC1 3) chain A residue 1099 type sequence E description BINDING SITE FOR RESIDUE KRG A 1 source : AC1 4) chain A residue 1102 type sequence Y description BINDING SITE FOR RESIDUE KRG A 1 source : AC1 5) chain A residue 1139 type sequence K description BINDING SITE FOR RESIDUE KRG A 1 source : AC1 6) chain A residue 1110 type sequence P description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 7) chain A residue 1113 type sequence Q description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 8) chain A residue 1115 type sequence V description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 9) chain A residue 1122 type sequence I description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 10) chain A residue 1168 type sequence N description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 11) chain A residue 1174 type sequence V description BINDING SITE FOR RESIDUE KRG A 2 source : AC2 12) chain A residue 1103 type sequence R description BINDING SITE FOR RESIDUE EDO A 1198 source : AC3 13) chain A residue 1112 type sequence R description BINDING SITE FOR RESIDUE EDO A 1198 source : AC3 14) chain A residue 1151 type sequence W description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 15) chain A residue 1154 type sequence V description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 16) chain A residue 1158 type sequence W description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 17) chain A residue 1185 type sequence F description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 18) chain A residue 1186 type sequence E description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 19) chain A residue 1193 type sequence M description BINDING SITE FOR RESIDUE KRG B 2 source : AC4 20) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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