eF-site/Summary 3ss3-C

eF-site ID	3ss3-C
PDB Code	3ss3
Chain	C

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Title	Crystal structure of mouse Glutaminase C, ligand-free form
Classification	HYDROLASE
Compound	Glutaminase C
Source	null (Q69ZX9_MOUSE)

Sequence	C:	LEDLLFYTIQEKIPVHKFITALKSTGLRTSDPRLKECMDM LRLTMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTS HIDELYESAKKQSGGKVADKFSPDLWGVSVCTVDGQRHSI GDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSG FLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQF LNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCF PEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCP ITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAK SGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDL VSLCNFHNYDNLRHFAKKLDPRR

Description

Functional site


1)	chain	C
	residue	290
	type
	sequence	Q
	description	BINDING SITE FOR RESIDUE CL C 3
	source	: AC3

2)	chain	C
	residue	291
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CL C 3
	source	: AC3

3)	chain	C
	residue	471
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE CL C 3
	source	: AC3

4)	chain	C
	residue	489
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE CL C 3
	source	: AC3

5)	chain	C
	residue	285
	type	BINDING
	sequence	V
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

6)	chain	C
	residue	334
	type	BINDING
	sequence	P
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

7)	chain	C
	residue	380
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

8)	chain	C
	residue	387
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

9)	chain	C
	residue	413
	type	BINDING
	sequence	V
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

10)	chain	C
	residue	465
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

11)	chain	C
	residue	483
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:22228304, ECO:0007744\|PDB:3SS5
	source	Swiss-Prot : SWS_FT_FI1

12)	chain	C
	residue	163
	type	MOD_RES
	sequence	K
	description	N6-succinyllysine => ECO:0007744\|PubMed:23806337
	source	Swiss-Prot : SWS_FT_FI2

13)	chain	C
	residue	310
	type	MOD_RES
	sequence	V
	description	N6-acetyllysine => ECO:0000250\|UniProtKB:O94925
	source	Swiss-Prot : SWS_FT_FI3