eF-site ID 3sm9-A PDB Code 3sm9 Chain A click to enlarge Title Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist Classification SIGNALING PROTEIN Compound Metabotropic glutamate receptor 3 Source Homo sapiens (Human) (GRM3_HUMAN) Sequence A:  RREIKIEGDLVLGGLFPINEKGTTEECGRINEDRGIQRLE AMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSL EFVRASLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYAS TSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYV STVASEGDYGETGIEAFEQEARLRNISIATAEKVGRIRKS YDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASF TWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDR YFQSLNPYNNHRNPWFRDFWEQKFQCSLQNHRRVCDKHLA IDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKL CDAMKILDGKKLYKDYLLKINFTAPFNDSIVKFDTFGDGM GRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWS Description Functional site 1) chain A residue 131 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 480 source : AC1 2) chain A residue 134 type sequence N description BINDING SITE FOR RESIDUE SO4 A 480 source : AC1 3) chain A residue 137 type sequence R description BINDING SITE FOR RESIDUE SO4 A 480 source : AC1 4) chain A residue 76 type sequence R description BINDING SITE FOR RESIDUE SO4 A 481 source : AC2 5) chain A residue 77 type sequence D description BINDING SITE FOR RESIDUE SO4 A 481 source : AC2 6) chain A residue 78 type sequence T description BINDING SITE FOR RESIDUE SO4 A 481 source : AC2 7) chain A residue 252 type sequence R description BINDING SITE FOR RESIDUE SO4 A 482 source : AC3 8) chain A residue 253 type sequence S description BINDING SITE FOR RESIDUE SO4 A 482 source : AC3 9) chain A residue 254 type sequence D description BINDING SITE FOR RESIDUE SO4 A 482 source : AC3 10) chain A residue 281 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 483 source : AC4 11) chain A residue 282 type sequence E description BINDING SITE FOR RESIDUE SO4 A 483 source : AC4 12) chain A residue 283 type sequence S description BINDING SITE FOR RESIDUE SO4 A 483 source : AC4 13) chain A residue 432 type sequence D description BINDING SITE FOR RESIDUE SO4 A 484 source : AC5 14) chain A residue 433 type sequence T description BINDING SITE FOR RESIDUE SO4 A 484 source : AC5 15) chain A residue 434 type sequence F description BINDING SITE FOR RESIDUE SO4 A 484 source : AC5 16) chain A residue 39 type sequence R description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 17) chain A residue 43 type sequence R description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 18) chain A residue 124 type sequence S description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 19) chain A residue 125 type sequence Y description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 20) chain A residue 126 type sequence S description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 21) chain A residue 147 type sequence A description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 22) chain A residue 148 type sequence S description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 23) chain A residue 149 type sequence T description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 24) chain A residue 197 type sequence Y description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 25) chain A residue 364 type sequence K description BINDING SITE FOR RESIDUE Z99 A 485 source : AC6 26) chain A residue 73 type sequence T description BINDING SITE FOR RESIDUE CL A 486 source : AC7 27) chain A residue 124 type sequence S description BINDING SITE FOR RESIDUE CL A 486 source : AC7 28) chain A residue 125 type sequence Y description BINDING SITE FOR RESIDUE CL A 486 source : AC7 29) chain A residue 128 type sequence V description BINDING SITE FOR RESIDUE CL A 486 source : AC7 30) chain A residue 126 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 147 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 197 type BINDING sequence Y description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 276 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 34) chain A residue 364 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 35) chain A residue 184 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 36) chain A residue 267 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 37) chain A residue 389 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 38) chain A residue 414 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 39) chain A residue 132-150 type prosite sequence VANLLRLFQIPQISYASTS description G_PROTEIN_RECEP_F3_1 G-protein coupled receptors family 3 signature 1. VaNLLrLFqIPQISyASTS source prosite : PS00979

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