eF-site ID 3shj-Y PDB Code 3shj Chain Y click to enlarge Title Proteasome in complex with hydroxyurea derivative HU10 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome component Y7 Source ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 2) chain Y residue 2 type sequence T description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 3) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 4) chain Y residue 23 type sequence G description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 5) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 6) chain Y residue 129 type sequence S description BINDING SITE FOR RESIDUE MES Y 1L source : AC3 7) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 8) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 9) chain Y residue 19 type sequence R description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 10) chain Y residue 20 type sequence A description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 11) chain Y residue 21 type sequence T description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 12) chain Y residue 31 type sequence V description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 13) chain Y residue 45 type sequence M description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 14) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 15) chain Y residue 49 type sequence A description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 16) chain Y residue 53 type sequence Q description BINDING SITE FOR RESIDUE H10 Y 2I source : AC4 17) chain Y residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

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