|
|
eF-site ID
|
3shj-V |
|
PDB Code
|
3shj |
|
Chain
|
V |
|
click to enlarge
|
|
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Title
|
Proteasome in complex with hydroxyurea derivative HU10 |
|
Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome component Y7 |
|
Source
|
ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
V: |
TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK
IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL
QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD
VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ
AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ
KSYKFPRGTTAVLKESIVNICD
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
V |
| residue |
1 |
| type |
catalytic |
| sequence |
T
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
2)
|
chain |
V |
| residue |
17 |
| type |
catalytic |
| sequence |
D
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
3)
|
chain |
V |
| residue |
19 |
| type |
catalytic |
| sequence |
R
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
4)
|
chain |
V |
| residue |
33 |
| type |
catalytic |
| sequence |
K
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
5)
|
chain |
V |
| residue |
47 |
| type |
catalytic |
| sequence |
G
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
6)
|
chain |
V |
| residue |
129 |
| type |
catalytic |
| sequence |
S
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
7)
|
chain |
V |
| residue |
166 |
| type |
catalytic |
| sequence |
D
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
8)
|
chain |
V |
| residue |
169 |
| type |
catalytic |
| sequence |
S
|
| description |
177
|
| source |
MCSA : MCSA2
|
|
|
|