eF-site ID 3shj-K PDB Code 3shj Chain K click to enlarge Title Proteasome in complex with hydroxyurea derivative HU10 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome component Y7 Source ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence K:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain K residue 1 type sequence T description BINDING SITE FOR RESIDUE MES K 1L source : AC1 2) chain K residue 2 type sequence T description BINDING SITE FOR RESIDUE MES K 1L source : AC1 3) chain K residue 21 type sequence T description BINDING SITE FOR RESIDUE MES K 1L source : AC1 4) chain K residue 23 type sequence G description BINDING SITE FOR RESIDUE MES K 1L source : AC1 5) chain K residue 47 type sequence G description BINDING SITE FOR RESIDUE MES K 1L source : AC1 6) chain K residue 128 type sequence G description BINDING SITE FOR RESIDUE MES K 1L source : AC1 7) chain K residue 129 type sequence S description BINDING SITE FOR RESIDUE MES K 1L source : AC1 8) chain K residue 1 type sequence T description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 9) chain K residue 1 type sequence T description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 10) chain K residue 19 type sequence R description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 11) chain K residue 20 type sequence A description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 12) chain K residue 21 type sequence T description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 13) chain K residue 31 type sequence V description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 14) chain K residue 45 type sequence M description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 15) chain K residue 47 type sequence G description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 16) chain K residue 49 type sequence A description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 17) chain K residue 53 type sequence Q description BINDING SITE FOR RESIDUE H10 K 2I source : AC2 18) chain K residue 4-51 type prosite sequence LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLG TMAGGAAD description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkGknCVVLGCErrstlklqdtritps.KvskidshvvlsfsGlnAD source prosite : PS00854 19) chain K residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

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