|
|
eF-site ID
|
3se9-H |
|
PDB Code
|
3se9 |
|
Chain
|
H |
|
click to enlarge
|
|
|
Title
|
Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 |
|
Classification
|
VIRAL PROTEIN/IMMUNE SYSTEM |
|
Compound
|
HIV-1 Clade AE strain 93TH057 gp120 |
|
Source
|
(3SE9) |
|
|
Sequence
|
H: |
QVQLVQSGSGVKKPGASVRVSCWTSEDIFERTELIHWVRQ
APGQGLEWIGWVKTVTGAVNFGSPDFRQRVSLTRDRDLFT
AHMDIRGLTQGDTATYFCARQKFYTGGQGWYFDLWGRGTL
IVVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG
TQTYICNVNHKPSNTKVDKKVEPKS
|
|
|
Description
|
(1) |
HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC-PG04, Light chain of antibody VRC-PG04
|
|
Functional site
|
|
|
1)
|
chain |
H |
| residue |
194-200 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
|