eF-site ID 3se9-GHL PDB Code 3se9 Chain G, H, L click to enlarge Title Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120 Classification VIRAL PROTEIN/IMMUNE SYSTEM Compound HIV-1 Clade AE strain 93TH057 gp120 Source (3SE9) Sequence G:  VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQE IHLENVTENFNMWKNNMVEQMQEDVISLWDQSLQPCVKLT GGSVIKQACPKISFDPIPIHYCTPAGYVILKCNDKNFNGT GPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSEN LTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKW NKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCR GEFFYCNTTQLFNNTCIGMKGCNGTITLPCKIKQIINMWQ GTGQAMYAPPIDGKINCVSNITGILLTRDGGANNTSNETF RPGGGNIKDNWRSELYKYKVVQIE H:  QVQLVQSGSGVKKPGASVRVSCWTSEDIFERTELIHWVRQ APGQGLEWIGWVKTVTGAVNFGSPDFRQRVSLTRDRDLFT AHMDIRGLTQGDTATYFCARQKFYTGGQGWYFDLWGRGTL IVVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG TQTYICNVNHKPSNTKVDKKVEPKS L:  EIVLTQSPGTLSLSPGETASLSCTAASYGHMTWYQKKPGQ PPKLLIFATSKRASGIPDRFSGSQFGKQYTLTITRMEPED FARYYCQQLEFFGQGTRLEIRRTVAAPSVFIFPPSDEQLK SGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQ DSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVT KSFNRGEC Description (1)  HIV-1 Clade AE strain 93TH057 gp120, Heavy chain of antibody VRC-PG04, Light chain of antibody VRC-PG04 Functional site 1) chain H residue 194-200 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 2) chain L residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

Display surface Download Links