eF-site ID 3s9y-A PDB Code 3s9y Chain A click to enlarge Title Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP Classification LYASE Compound Orotidine 5'-phosphate decarboxylase Source null (Q8IJH3_PLAF7) Sequence A:  SGLVPRGSMGFKVKLEKRRNAINTCLCIGLDPDEKDIENF MKNEKENNYNNIKKNLKEKYINNVSIKKDILLKAPDNIIR EEKSEEFFYFFNHFCFYIINETNKYALTFKMNFAFYIPYG SVGIDVLKNVFDYLYELNIPTILDMKINDIGNTVKNYRKF IFEYLKSDSCTVNIYMGTNMLKDICYDEEKNKYYSAFVLV KTTNPDSAIFQKNLSLDNKQAYVIMAQEALNMSSYLNLEQ NNEFIGFVVGANSYDEMNYIRTYFPNCYILSPGIGAQNGD LHKTLTNGYHKSYEKILINIGRAITKNPYPQKAAQMYYDQ INAILKQNMES Description Functional site 1) chain A residue 23 type sequence D description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 2) chain A residue 102 type sequence K description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 3) chain A residue 104 type sequence N description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 4) chain A residue 136 type sequence D description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 5) chain A residue 138 type sequence K description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 6) chain A residue 191 type sequence L description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 7) chain A residue 194 type sequence T description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 8) chain A residue 195 type sequence T description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 9) chain A residue 240 type sequence V description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 10) chain A residue 264 type sequence P description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 11) chain A residue 269 type sequence Q description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 12) chain A residue 293 type sequence G description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 13) chain A residue 294 type sequence R description BINDING SITE FOR RESIDUE FNU A 324 source : AC1 14) chain A residue 141 type sequence D description BINDING SITE FOR RESIDUE FNU B 324 source : AC2 15) chain A residue 142 type sequence I description BINDING SITE FOR RESIDUE FNU B 324 source : AC2 16) chain A residue 145 type sequence T description BINDING SITE FOR RESIDUE FNU B 324 source : AC2 17) chain A residue 142 type sequence I description BINDING SITE FOR RESIDUE PEG B 3001 source : AC5 18) chain A residue 143 type sequence G description BINDING SITE FOR RESIDUE PEG B 3001 source : AC5 19) chain A residue 171 type sequence N description BINDING SITE FOR RESIDUE PEG B 3001 source : AC5 20) chain A residue 205 type sequence N description BINDING SITE FOR RESIDUE P6G C 3002 source : AC8 21) chain A residue 133-146 type prosite sequence TILDMKINDIGNTV description OMPDECASE Orotidine 5'-phosphate decarboxylase active site. TIlDmKinDIGnTV source prosite : PS00156

Display surface Download Links