eF-site ID 3s3k-B PDB Code 3s3k Chain B click to enlarge Title Crystal structure of the catalytic domain of PTP10D from Drosophila melanogaster with a small molecular inhibitor para-NitroCatechol Sulphate Classification HYDROLASE/HYDROLASE INHIBITOR Compound Tyrosine-protein phosphatase 10D Source Drosophila melanogaster (Fruit fly) (PTP10_DROME) Sequence B:  MASRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQ PCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDY INANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRA IVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSH YADWVMTEFMLCRGSEQRILRHFHFTTWPDFGVPNPPQTL VRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITLDRILQ QINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLA VLEGK Description Functional site 1) chain B residue 154 type sequence K description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 2) chain B residue 242 type sequence C description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 3) chain B residue 243 type sequence S description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 4) chain B residue 244 type sequence A description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 5) chain B residue 245 type sequence G description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 6) chain B residue 246 type sequence V description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 7) chain B residue 248 type sequence R description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 8) chain B residue 286 type sequence Q description BINDING SITE FOR RESIDUE CSN B 308 source : AC1 9) chain B residue 242 type ACT_SITE sequence C description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000255|PROSITE-ProRule:PRU10044 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 210 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 242 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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